Open Source Drug Discovery: Highly Potent Antimalarial Compounds Derived from the Tres Cantos Arylpyrroles

[Image: see text] The development of new antimalarial compounds remains a pivotal part of the strategy for malaria elimination. Recent large-scale phenotypic screens have provided a wealth of potential starting points for hit-to-lead campaigns. One such public set is explored, employing an open sour...

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出版年:ACS Cent Sci
主要な著者: Williamson, Alice E., Ylioja, Paul M., Robertson, Murray N., Antonova-Koch, Yevgeniya, Avery, Vicky, Baell, Jonathan B., Batchu, Harikrishna, Batra, Sanjay, Burrows, Jeremy N., Bhattacharyya, Soumya, Calderon, Felix, Charman, Susan A., Clark, Julie, Crespo, Benigno, Dean, Matin, Debbert, Stefan L., Delves, Michael, Dennis, Adelaide S. M., Deroose, Frederik, Duffy, Sandra, Fletcher, Sabine, Giaever, Guri, Hallyburton, Irene, Gamo, Francisco-Javier, Gebbia, Marinella, Guy, R. Kiplin, Hungerford, Zoe, Kirk, Kiaran, Lafuente-Monasterio, Maria J., Lee, Anna, Meister, Stephan, Nislow, Corey, Overington, John P., Papadatos, George, Patiny, Luc, Pham, James, Ralph, Stuart A., Ruecker, Andrea, Ryan, Eileen, Southan, Christopher, Srivastava, Kumkum, Swain, Chris, Tarnowski, Matthew J., Thomson, Patrick, Turner, Peter, Wallace, Iain M., Wells, Timothy N. C., White, Karen, White, Laura, Willis, Paul, Winzeler, Elizabeth A., Wittlin, Sergio, Todd, Matthew H.
フォーマット: Artigo
言語:Inglês
出版事項: American Chemical Society 2016
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5084075/
https://ncbi.nlm.nih.gov/pubmed/27800551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acscentsci.6b00086
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