Open Source Drug Discovery: Highly Potent Antimalarial Compounds Derived from the Tres Cantos Arylpyrroles

[Image: see text] The development of new antimalarial compounds remains a pivotal part of the strategy for malaria elimination. Recent large-scale phenotypic screens have provided a wealth of potential starting points for hit-to-lead campaigns. One such public set is explored, employing an open sour...

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Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:ACS Cent Sci
Κύριοι συγγραφείς: Williamson, Alice E., Ylioja, Paul M., Robertson, Murray N., Antonova-Koch, Yevgeniya, Avery, Vicky, Baell, Jonathan B., Batchu, Harikrishna, Batra, Sanjay, Burrows, Jeremy N., Bhattacharyya, Soumya, Calderon, Felix, Charman, Susan A., Clark, Julie, Crespo, Benigno, Dean, Matin, Debbert, Stefan L., Delves, Michael, Dennis, Adelaide S. M., Deroose, Frederik, Duffy, Sandra, Fletcher, Sabine, Giaever, Guri, Hallyburton, Irene, Gamo, Francisco-Javier, Gebbia, Marinella, Guy, R. Kiplin, Hungerford, Zoe, Kirk, Kiaran, Lafuente-Monasterio, Maria J., Lee, Anna, Meister, Stephan, Nislow, Corey, Overington, John P., Papadatos, George, Patiny, Luc, Pham, James, Ralph, Stuart A., Ruecker, Andrea, Ryan, Eileen, Southan, Christopher, Srivastava, Kumkum, Swain, Chris, Tarnowski, Matthew J., Thomson, Patrick, Turner, Peter, Wallace, Iain M., Wells, Timothy N. C., White, Karen, White, Laura, Willis, Paul, Winzeler, Elizabeth A., Wittlin, Sergio, Todd, Matthew H.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: American Chemical Society 2016
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5084075/
https://ncbi.nlm.nih.gov/pubmed/27800551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acscentsci.6b00086
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