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A different mechanism for the inhibition of the carboxyltransferase domain of acetyl-coenzyme A carboxylase by tepraloxydim

Acetyl-CoA carboxylases (ACCs) are crucial metabolic enzymes and are attractive targets for drug discovery. Haloxyfop and tepraloxydim belong to two distinct classes of commercial herbicides and kill sensitive plants by inhibiting the carboxyltransferase (CT) activity of ACC. Our earlier structural...

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Detalhes bibliográficos
Main Authors: Xiang, Song, Callaghan, Matthew M., Watson, Keith G., Tong, Liang
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2791573/
https://ncbi.nlm.nih.gov/pubmed/19926852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0908431106
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