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Molecular basis for the inhibition of the carboxyltransferase domain of acetyl-coenzyme-A carboxylase by haloxyfop and diclofop

Acetyl-CoA carboxylases (ACCs) are crucial for the metabolism of fatty acids, making these enzymes important targets for the development of therapeutics against obesity, diabetes, and other diseases. The carboxyltransferase (CT) domain of ACC is the site of action of commercial herbicides, such as h...

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Detalhes bibliográficos
Main Authors: Zhang, Hailong, Tweel, Benjamin, Tong, Liang
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC395897/
https://ncbi.nlm.nih.gov/pubmed/15079078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0400891101
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