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Mechanism for the inhibition of the carboxyltransferase domain of acetyl-coenzyme A carboxylase by pinoxaden

Acetyl-CoA carboxylases (ACCs) are crucial metabolic enzymes and have been targeted for drug development against obesity, diabetes, and other diseases. The carboxyltransferase (CT) domain of this enzyme is the site of action for three different classes of herbicides, as represented by haloxyfop, tep...

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Autori principali: Yu, Linda P. C., Kim, Yi Seul, Tong, Liang
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3009786/
https://ncbi.nlm.nih.gov/pubmed/21135213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1012039107
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