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OTUB1 modulates c-IAP1 stability to regulate signalling pathways
The cellular inhibitor of apoptosis (c-IAP) proteins are E3 ubiquitin ligases that are critical regulators of tumour necrosis factor (TNF) receptor (TNFR)-mediated signalling. Through their E3 ligase activity c-IAP proteins promote ubiquitination of receptor-interaction protein 1 (RIP1), NF-κB-induc...
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| Autors principals: | , , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
European Molecular Biology Organization
2013
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3630360/ https://ncbi.nlm.nih.gov/pubmed/23524849 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2013.62 |
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