OTUB1 modulates c-IAP1 stability to regulate signalling pathways

The cellular inhibitor of apoptosis (c-IAP) proteins are E3 ubiquitin ligases that are critical regulators of tumour necrosis factor (TNF) receptor (TNFR)-mediated signalling. Through their E3 ligase activity c-IAP proteins promote ubiquitination of receptor-interaction protein 1 (RIP1), NF-κB-induc...

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Main Authors: Goncharov, Tatiana, Niessen, Kyle, de Almagro, Maria Cristina, Izrael-Tomasevic, Anita, Fedorova, Anna V, Varfolomeev, Eugene, Arnott, David, Deshayes, Kurt, Kirkpatrick, Donald S, Vucic, Domagoj
Formato: Artigo
Idioma:Inglês
Publicado: European Molecular Biology Organization 2013
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3630360/
https://ncbi.nlm.nih.gov/pubmed/23524849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2013.62
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