c-IAP1 and UbcH5 promote K11-linked polyubiquitination of RIP1 in TNF signalling

Ubiquitin ligases are critical components of the ubiquitination process that determine substrate specificity and, in collaboration with E2 ubiquitin-conjugating enzymes, regulate the nature of polyubiquitin chains assembled on their substrates. Cellular inhibitor of apoptosis (c-IAP1 and c-IAP2) pro...

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Main Authors: Dynek, Jasmin N, Goncharov, Tatiana, Dueber, Erin C, Fedorova, Anna V, Izrael-Tomasevic, Anita, Phu, Lilian, Helgason, Elizabeth, Fairbrother, Wayne J, Deshayes, Kurt, Kirkpatrick, Donald S, Vucic, Domagoj
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3018797/
https://ncbi.nlm.nih.gov/pubmed/21113135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2010.300
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