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Cellular IAP proteins and LUBAC differentially regulate necrosome-associated RIP1 ubiquitination

Necroptosis is a caspase-independent regulated type of cell death that relies on receptor-interacting protein kinases RIP1 (receptor-interacting protein kinases 1) and RIP3. Tumor necrosis factor-α (TNFα)-stimulated assembly of the TNFR1 (TNF receptor 1)-associated signaling complex leads to the rec...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: de Almagro, M C, Goncharov, T, Newton, K, Vucic, D
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4669837/
https://ncbi.nlm.nih.gov/pubmed/26111062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2015.158
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