Coordinated ubiquitination and phosphorylation of RIP1 regulates necroptotic cell death

Proper regulation of cell death signaling is crucial for the maintenance of homeostasis and prevention of disease. A caspase-independent regulated form of cell death called necroptosis is rapidly emerging as an important mediator of a number of human pathologies including inflammatory bowel disease...

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Veröffentlicht in:Cell Death Differ
Hauptverfasser: de Almagro, M Cristina, Goncharov, Tatiana, Izrael-Tomasevic, Anita, Duttler, Stefanie, Kist, Matthias, Varfolomeev, Eugene, Wu, Xiumin, Lee, Wyne P, Murray, Jeremy, Webster, Joshua D, Yu, Kebing, Kirkpatrick, Donald S, Newton, Kim, Vucic, Domagoj
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2017
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Original Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5260504/
https://ncbi.nlm.nih.gov/pubmed/27518435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2016.78
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