c-IAP1 and c-IAP2 Are Critical Mediators of Tumor Necrosis Factor α (TNFα)-induced NF-κB Activation

The inhibitor of apoptosis (IAP) proteins are a family of anti-apoptotic regulators found in viruses and metazoans. c-IAP1 and c-IAP2 are recruited to tumor necrosis factor receptor 1 (TNFR1)-associated complexes where they can regulate receptor-mediated signaling. Both c-IAP1 and c-IAP2 have been i...

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Detalhes bibliográficos
Main Authors: Varfolomeev, Eugene, Goncharov, Tatiana, Fedorova, Anna V., Dynek, Jasmin N., Zobel, Kerry, Deshayes, Kurt, Fairbrother, Wayne J., Vucic, Domagoj
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2008
Assuntos:
Accelerated Publications
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3259840/
https://ncbi.nlm.nih.gov/pubmed/18621737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.C800128200
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