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Both cIAP1 and cIAP2 regulate TNFα-mediated NF-κB activation
The cellular inhibitor of apoptosis 1 and 2 (cIAP1 and cIAP2) proteins have been implicated in the activation of NF-κB by TNFα; however, genetic deletion of either cIAP1 or 2 did not support a physiologically relevant role, perhaps because of functional redundancy. To address this, we used combined...
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| Autors principals: | , , , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
2008
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2575330/ https://ncbi.nlm.nih.gov/pubmed/18697935 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0711122105 |
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