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The RING Domain of cIAP1 Mediates the Degradation of RING-bearing Inhibitor of Apoptosis Proteins by Distinct Pathways

The Inhibitor of Apoptosis proteins (IAPs) are key repressors of apoptosis. Several IAP proteins contain a RING domain that functions as an E3 ubiquitin ligase involved in the ubiquitin-proteasome pathway. Here we investigated the interplay of ubiquitin-proteasome pathway and RING-mediated IAP turno...

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Detalhes bibliográficos
Main Authors: Cheung, Herman H., Plenchette, Stéphanie, Kern, Chris J., Mahoney, Douglas J., Korneluk, Robert G.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2441678/
https://ncbi.nlm.nih.gov/pubmed/18434593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E08-01-0107
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