Protein NMR spectroscopy : principles and practice /

Por Cavanagh, John., Fairbrother, Wayne J., Palmer III, Arthur G., Rance, Mark., Skelton, Nicholas J.
Publicado em c200

c-IAP1 and c-IAP2 Are Critical Mediators of Tumor Necrosis Factor α (TNFα)-induced NF-κB Activation

Por Varfolomeev, Eugene, Goncharov, Tatiana, Fedorova, Anna V., Dynek, Jasmin N., Zobel, Kerry, Deshayes, Kurt, Fairbrother, Wayne J., Vucic, Domagoj
Publicado em 2008

The structure of interleukin-33 and its interaction with the ST2 and IL-1RAcP receptors – insight into the arrangement of heterotrimeric interleukin-1 signaling complexes

Por Lingel, Andreas, Weiss, Thomas M., Niebuhr, Marc, Pan, Borlan, Appleton, Brent A., Wiesmann, Christian, Bazan, J. Fernando, Fairbrother, Wayne J.
Publicado em 2009

Murine Insulin Growth Factor-like (IGFL) and Human IGFL1 Proteins Are Induced in Inflammatory Skin Conditions and Bind to a Novel Tumor Necrosis Factor Receptor Family Member, IGFL...

Por Lobito, Adrian A., Ramani, Sree R., Tom, Irene, Bazan, J. Fernando, Luis, Elizabeth, Fairbrother, Wayne J., Ouyang, Wenjun, Gonzalez, Lino C.
Publicado em 2011

The PYRIN domain: A member of the death domain-fold superfamily

Por Fairbrother, Wayne J., Gordon, Nathaniel C., Humke, Eric W., O'Rourke, Karen M., Starovasnik, Melissa A., Yin, Jian-Ping, Dixit, Vishva M.
Publicado em 2001

X Chromosome-linked Inhibitor of Apoptosis Regulates Cell Death Induction by Proapoptotic Receptor Agonists

Por Varfolomeev, Eugene, Alicke, Bruno, Elliott, J. Michael, Zobel, Kerry, West, Kristina, Wong, Harvey, Scheer, Justin M., Ashkenazi, Avi, Gould, Stephen E., Fairbrother, Wayne J., Vucic, Domagoj
Publicado em 2009

c-IAP1 and UbcH5 promote K11-linked polyubiquitination of RIP1 in TNF signalling

Por Dynek, Jasmin N, Goncharov, Tatiana, Dueber, Erin C, Fedorova, Anna V, Izrael-Tomasevic, Anita, Phu, Lilian, Helgason, Elizabeth, Fairbrother, Wayne J, Deshayes, Kurt, Kirkpatrick, Donald S, Vucic, Domagoj
Publicado em 2010

Engineering ML-IAP to produce an extraordinarily potent caspase 9 inhibitor: implications for Smac-dependent anti-apoptotic activity of ML-IAP

Por Vucic, Domagoj, Franklin, Matthew C., Wallweber, Heidi J. A., Das, Kanad, Eckelman, Brendan P., Shin, Hwain, Elliott, Linda O., Kadkhodayan, Saloumeh, Deshayes, Kurt, Salvesen, Guy S., Fairbrother, Wayne J.
Publicado em 2004

Conformational dynamics control ubiquitin-deubiquitinase interactions and influence in vivo signaling

Por Phillips, Aaron H., Zhang, Yingnan, Cunningham, Christian N., Zhou, Lijuan, Forrest, William F., Liu, Peter S., Steffek, Micah, Lee, James, Tam, Christine, Helgason, Elizabeth, Murray, Jeremy M., Kirkpatrick, Donald S., Fairbrother, Wayne J., Corn, Jacob E.
Publicado em 2013

Structure-Guided Rescaffolding of Selective Antagonists of BCL-X(L)

Por Koehler, Michael F. T., Bergeron, Philippe, Choo, Edna F., Lau, Kevin, Ndubaku, Chudi, Dudley, Danette, Gibbons, Paul, Sleebs, Brad E., Rye, Carl S., Nikolakopoulos, George, Bui, Chinh, Kulasegaram, Sanji, Kersten, Wilhelmus J. A., Smith, Brian J., Czabotar, Peter E., Colman, Peter M., Huang, David C. S., Baell, Jonathan B., Watson, Keith G., Hasvold, Lisa, Tao, Zhi-Fu, Wang, Le, Souers, Andrew J., Elmore, Steven W., Flygare, John A., Fairbrother, Wayne J., Lessene, Guillaume
Publicado em 2014

The Discovery of a Potent Small-Molecule Antagonist of Inhibitor of Apoptosis (IAP) Proteins and Clinical Candidate for the Treatment of Cancer (GDC-0152)

Por Flygare, John A., Beresini, Maureen, Budha, Nageshwar, Chan, Helen, Chan, Iris T., Cheeti, Sravanthi, Cohen, Frederick, Deshayes, Kurt, Doerner, Karl, Eckhardt, S. Gail, Elliott, Linda O., Feng, Bainian, Franklin, Matthew C., Reisner, Stacy Frankovitz, Gazzard, Lewis, Halladay, Jason, Hymowitz, Sarah G., La, Hank, LoRusso, Patricia, Maurer, Brigitte, Murray, Lesley, Plise, Emile, Quan, Clifford, Stephan, Jean-Philippe, Shin, Young G., Tom, Jeffrey, Tsui, Vickie, Um, Joanne, Varfolomeev, Eugene, Vucic, Domagoj, Wagner, Andrew J., Wallweber, Heidi J.A., Wang, Lan, Ware, Joseph, Wen, Zhaoyang, Wong, Harvey, Wong, Jonathan M., Wong, Melisa, Wong, Susan, Yu, Ron, Zobel, Kerry, Fairbrother, Wayne J.
Publicado em 2012

Discovery of a Potent and Selective BCL-X(L) Inhibitor with in Vivo Activity

Por Tao, Zhi-Fu, Hasvold, Lisa, Wang, Le, Wang, Xilu, Petros, Andrew M., Park, Chang H., Boghaert, Erwin R., Catron, Nathaniel D., Chen, Jun, Colman, Peter M., Czabotar, Peter E., Deshayes, Kurt, Fairbrother, Wayne J., Flygare, John A., Hymowitz, Sarah G., Jin, Sha, Judge, Russell A., Koehler, Michael F. T., Kovar, Peter J., Lessene, Guillaume, Mitten, Michael J., Ndubaku, Chudi O., Nimmer, Paul, Purkey, Hans E., Oleksijew, Anatol, Phillips, Darren C., Sleebs, Brad E., Smith, Brian J., Smith, Morey L., Tahir, Stephen K., Watson, Keith G., Xiao, Yu, Xue, John, Zhang, Haichao, Zobel, Kerry, Rosenberg, Saul H., Tse, Chris, Leverson, Joel D., Elmore, Steven W., Souers, Andrew J.
Publicado em 2014