Immunization associated with primary tumor growth leads to rejection of commonly used syngeneic tumors upon tumor rechallenge

per Alicke, Bruno, Totpal, Klara, Schartner, Jill M, Berkley, Amy M, Lehar, Sophie M, Capietto, Aude-Hélène, Cubas, Rafael A, Gould, Stephen E
Publicat a J Immunother Cancer (2020)

X Chromosome-linked Inhibitor of Apoptosis Regulates Cell Death Induction by Proapoptotic Receptor Agonists

per Varfolomeev, Eugene, Alicke, Bruno, Elliott, J. Michael, Zobel, Kerry, West, Kristina, Wong, Harvey, Scheer, Justin M., Ashkenazi, Avi, Gould, Stephen E., Fairbrother, Wayne J., Vucic, Domagoj
Publicat 2009

Treatment of Medulloblastoma with Hedgehog Pathway Inhibitor GDC-0449

per Rudin, Charles M., Hann, Christine L., Laterra, John, Yauch, Robert L., Callahan, Christopher A., Fu, Ling, Holcomb, Thomas, Stinson, Jeremy, Gould, Stephen E., Coleman, Barbara, LoRusso, Patricia M., Von Hoff, Daniel D., de Sauvage, Frederic J., Low, Jennifer A.
Publicat a N Engl J Med (2009)

Discovery of Clinical Development Candidate GDC-0084, a Brain Penetrant Inhibitor of PI3K and mTOR

per Heffron, Timothy P., Ndubaku, Chudi O., Salphati, Laurent, Alicke, Bruno, Cheong, Jonathan, Drobnick, Joy, Edgar, Kyle, Gould, Stephen E., Lee, Leslie B., Lesnick, John D., Lewis, Cristina, Nonomiya, Jim, Pang, Jodie, Plise, Emile G., Sideris, Steve, Wallin, Jeffrey, Wang, Lan, Zhang, Xiaolin, Olivero, Alan G.
Publicat a ACS Med Chem Lett (2016)

Smoothened Mutation Confers Resistance to a Hedgehog Pathway Inhibitor in Medulloblastoma

per Yauch, Robert L., Dijkgraaf, Gerrit J. P., Alicke, Bruno, Januario, Thomas, Ahn, Christina P., Holcomb, Thomas, Pujara, Kanan, Stinson, Jeremy, Callahan, Christopher A., Tang, Tracy, Bazan, J. Fernando, Kan, Zhengyan, Seshagiri, Somasekar, Hann, Christine L., Gould, Stephen E., Low, Jennifer A., Rudin, Charles M., de Sauvage, Frederic J.
Publicat a Science (2009)

Structure-Based Design of GNE-495, a Potent and Selective MAP4K4 Inhibitor with Efficacy in Retinal Angiogenesis

per Ndubaku, Chudi O., Crawford, Terry D., Chen, Huifen, Boggs, Jason W., Drobnick, Joy, Harris, Seth F., Jesudason, Rajiv, McNamara, Erin, Nonomiya, Jim, Sambrone, Amy, Schmidt, Stephen, Smyczek, Tanya, Vitorino, Philip, Wang, Lan, Wu, Ping, Yeung, Stacey, Chen, Jinhua, Chen, Kevin, Ding, Charles Z., Wang, Tao, Xu, Zijin, Gould, Stephen E., Murray, Lesley J., Ye, Weilan
Publicat a ACS Med Chem Lett (2015)

Pyrazolopyridine Inhibitors of B-Raf(V600E). Part 1: The Development of Selective, Orally Bioavailable, and Efficacious Inhibitors

per Wenglowsky, Steve, Ren, Li, Ahrendt, Kateri A., Laird, Ellen R., Aliagas, Ignacio, Alicke, Bruno, Buckmelter, Alex J., Choo, Edna F., Dinkel, Victoria, Feng, Bainian, Gloor, Susan L., Gould, Stephen E., Gross, Stefan, Gunzner-Toste, Janet, Hansen, Joshua D., Hatzivassiliou, Georgia, Liu, Bonnie, Malesky, Kim, Mathieu, Simon, Newhouse, Brad, Raddatz, Nicholas J., Ran, Yingqing, Rana, Sumeet, Randolph, Nikole, Risom, Tyler, Rudolph, Joachim, Savage, Scott, Selby, LeAnn T., Shrag, Michael, Song, Kyung, Sturgis, Hillary L., Voegtli, Walter C., Wen, Zhaoyang, Willis, Brandon S., Woessner, Richard D., Wu, Wen-I, Young, Wendy B., Grina, Jonas
Publicat 2011