Therapeutic Effect and Mechanisms of the Novel Monosulfactam 0073

Por Sun, Ying, Liao, Xueyuan, Huang, Zhigang, Xie, Yaliu, Liu, Yanbin, Ma, Cuicui, Jiang, Boguang, Zhang, Li, Yan, Yuhang, Li, Guobo, Cheng, Xingjun, Yin, Qi, Ding, Charles Z., Shen, Liang, Li, Jian, Chen, Shuhui, Wei, Yuquan, Wang, Zhenling, Wei, Xiawei
Publicado no Antimicrob Agents Chemother (2020)

Structure-Based Design of GNE-495, a Potent and Selective MAP4K4 Inhibitor with Efficacy in Retinal Angiogenesis

Por Ndubaku, Chudi O., Crawford, Terry D., Chen, Huifen, Boggs, Jason W., Drobnick, Joy, Harris, Seth F., Jesudason, Rajiv, McNamara, Erin, Nonomiya, Jim, Sambrone, Amy, Schmidt, Stephen, Smyczek, Tanya, Vitorino, Philip, Wang, Lan, Wu, Ping, Yeung, Stacey, Chen, Jinhua, Chen, Kevin, Ding, Charles Z., Wang, Tao, Xu, Zijin, Gould, Stephen E., Murray, Lesley J., Ye, Weilan
Publicado no ACS Med Chem Lett (2015)

Cell Active Hydroxylactam Inhibitors of Human Lactate Dehydrogenase with Oral Bioavailability in Mice

Por Purkey, Hans E., Robarge, Kirk, Chen, Jinhua, Chen, Zhongguo, Corson, Laura B., Ding, Charles Z., DiPasquale, Antonio G., Dragovich, Peter S., Eigenbrot, Charles, Evangelista, Marie, Fauber, Benjamin P., Gao, Zhenting, Ge, Hongxiu, Hitz, Anna, Ho, Qunh, Labadie, Sharada S., Lai, Kwong Wah, Liu, Wenfeng, Liu, Yajing, Li, Chiho, Ma, Shuguang, Malek, Shiva, O’Brien, Thomas, Pang, Jodie, Peterson, David, Salphati, Laurent, Sideris, Steve, Ultsch, Mark, Wei, BinQing, Yen, Ivana, Yue, Qin, Zhang, Huihui, Zhou, Aihe
Publicado no ACS Med Chem Lett (2016)

Discovery of Novel Oral Protein Synthesis Inhibitors of Mycobacterium tuberculosis That Target Leucyl-tRNA Synthetase

Por Palencia, Andrés, Li, Xianfeng, Bu, Wei, Choi, Wai, Ding, Charles Z., Easom, Eric E., Feng, Lisa, Hernandez, Vincent, Houston, Paul, Liu, Liang, Meewan, Maliwan, Mohan, Manisha, Rock, Fernando L., Sexton, Holly, Zhang, Suoming, Zhou, Yasheen, Wan, Baojie, Wang, Yuehong, Franzblau, Scott G., Woolhiser, Lisa, Gruppo, Veronica, Lenaerts, Anne J., O'Malley, Theresa, Parish, Tanya, Cooper, Christopher B., Waters, M. Gerard, Ma, Zhenkun, Ioerger, Thomas R., Sacchettini, James C., Rullas, Joaquín, Angulo-Barturen, Iñigo, Pérez-Herrán, Esther, Mendoza, Alfonso, Barros, David, Cusack, Stephen, Plattner, Jacob J., Alley, M. R. K.
Publicado no Antimicrob Agents Chemother (2016)