Testing of Experimental Compounds in a Relapse Model of Tuberculosis Using Granulocyte-Macrophage Colony-Stimulating Factor Gene-Disrupted Mice

Por Woolhiser, Lisa K., Hoff, Donald R., Marietta, Karen S., Orme, Ian M., Lenaerts, Anne J.
Publicado em 2009

Mouse Model for Efficacy Testing of Antituberculosis Agents via Intrapulmonary Delivery

Por Gonzalez-Juarrero, Mercedes, Woolhiser, Lisa K., Brooks, Elizabeth, DeGroote, Mary Ann, Lenaerts, Anne J.
Publicado em 2012

Evaluation of a 2-Pyridone, KRQ-10018, against Mycobacterium tuberculosis In Vitro and In Vivo

Por Lenaerts, Anne J., Bitting, Casey, Woolhiser, Lisa, Gruppo, Veronica, Marietta, Karen S., Johnson, Christine M., Orme, Ian M.
Publicado em 2008

Importance of Confirming Data on the In Vivo Efficacy of Novel Antibacterial Drug Regimens against Various Strains of Mycobacterium tuberculosis

Por De Groote, Mary A., Gruppo, Veronica, Woolhiser, Lisa K., Orme, Ian M., Gilliland, Janet C., Lenaerts, Anne J.
Publicado em 2012

Effects of P-MAPA Immunomodulator on Toll-Like Receptors and p53: Potential Therapeutic Strategies for Infectious Diseases and Cancer

Por Fávaro, Wagner J, Nunes, Odilon S, Seiva, Fabio RF, Nunes, Iseu S, Woolhiser, Lisa K, Durán, Nelson, Lenaerts, Anne J
Publicado em 2012

In Vivo Adaptation of the Wayne Model of Latent Tuberculosis

Por Woolhiser, Lisa, Tamayo, Marcela Henao, Wang, Baolin, Gruppo, Veronica, Belisle, John T., Lenaerts, Anne J., Basaraba, Randall J., Orme, Ian M.
Publicado em 2007

Novel Pyridopyrazine and Pyrimidothiazine Derivatives as FtsZ Inhibitors

Por Mathew, Bini, Srivastava, Shefali, Ross, Larry J., Suling, William J., White, E. Lucile, Woolhiser, Lisa K., Lenaerts, Anne J., Reynolds, Robert C.
Publicado em 2011

A Novel Metabolite of Antituberculosis Therapy Demonstrates Host Activation of Isoniazid and Formation of the Isoniazid-NAD(+) Adduct

Por Mahapatra, Sebabrata, Woolhiser, Lisa K., Lenaerts, Anne J., Johnson, John L., Eisenach, Kathleen D., Joloba, Moses L., Boom, W. Henry, Belisle, John T.
Publicado em 2012

Intracellular and in vivo evaluation of imidazo[2,1-b]thiazole-5-carboxamide anti-tuberculosis compounds

Por Moraski, Garrett C., Deboosère, Nathalie, Marshall, Kate L., Weaver, Heath A., Vandeputte, Alexandre, Hastings, Courtney, Woolhiser, Lisa, Lenaerts, Anne J., Brodin, Priscille, Miller, Marvin J.
Publicado no PLoS One (2020)

Comparative Studies Evaluating Mouse Models Used for Efficacy Testing of Experimental Drugs against Mycobacterium tuberculosis

Por De Groote, Mary A., Gilliland, Janet C., Wells, Colby L., Brooks, Elizabeth J., Woolhiser, Lisa K., Gruppo, Veronica, Peloquin, Charles A., Orme, Ian M., Lenaerts, Anne J.
Publicado em 2011

Discovery, Synthesis, and Biological Evaluation of Piperidinol analogs With Anti-tuberculosis Activity

Por Sun, Dianqing, Scherman, Michael S., Jones, Victoria, Hurdle, Julian G., Woolhiser, Lisa K., Knudson, Susan E., Lenaerts, Anne J., Slayden, Richard A., McNeil, Michael R., Lee, Richard E.
Publicado em 2009

Bayesian Models Leveraging Bioactivity and Cytotoxicity Information for Drug Discovery

Por Ekins, Sean, Reynolds, Robert C., Kim, Hiyun, Koo, Mi-Sun, Ekonomidis, Marilyn, Talaue, Meliza, Paget, Steve D., Woolhiser, Lisa K., Lenaerts, Anne J., Bunin, Barry A., Connell, Nancy, Freundlich, Joel S.
Publicado em 2013

Pentacyclic Nitrofurans with In Vivo Efficacy and Activity against Nonreplicating Mycobacterium tuberculosis

Por Rakesh, Bruhn, David F., Scherman, Michael S., Woolhiser, Lisa K., Madhura, Dora B., Maddox, Marcus M., Singh, Aman P., Lee, Robin B., Hurdle, Julian G., McNeil, Michael R., Lenaerts, Anne J., Meibohm, Bernd, Lee, Richard E.
Publicado em 2014

Discovery of a cofactor-independent inhibitor of Mycobacterium tuberculosis InhA

Por Xia, Yi, Zhou, Yasheen, Carter, David S, McNeil, Matthew B, Choi, Wai, Halladay, Jason, Berry, Pamela W, Mao, Weimin, Hernandez, Vincent, O'Malley, Theresa, Korkegian, Aaron, Sunde, Bjorn, Flint, Lindsay, Woolhiser, Lisa K, Scherman, Michael S, Gruppo, Veronica, Hastings, Courtney, Robertson, Gregory T, Ioerger, Thomas R, Sacchettini, Jim, Tonge, Peter J, Lenaerts, Anne J, Parish, Tanya, Alley, MRK
Publicado no Life Sci Alliance (2018)

Development of a Novel Lead that Targets M. tuberculosis Polyketide Synthase 13

Por Aggarwal, Anup, Parai, Maloy K., Shetty, Nishant, Wallis, Deeann, Woolhiser, Lisa, Hastings, Courtney, Dutta, Noton K., Galaviz, Stacy, Dhakal, Ramesh C., Shrestha, Rupesh, Wakabayashi, Shoko, Walpole, Chris, Matthews, David, Floyd, David, Scullion, Paul, Riley, Jennifer, Epemolu, Ola, Norval, Suzanne, Snavely, Thomas, Robertson, Gregory T., Rubin, Eric J., Ioerger, Thomas R., Sirgel, Frik A., van der Merwe, Ruben, van Helden, Paul D., Keller, Peter, Böttger, Erik C., Karakousis, Petros C., Lenaerts, Anne J., Sacchettini, James C.
Publicado no Cell (2017)

Discovery of Novel Oral Protein Synthesis Inhibitors of Mycobacterium tuberculosis That Target Leucyl-tRNA Synthetase

Por Palencia, Andrés, Li, Xianfeng, Bu, Wei, Choi, Wai, Ding, Charles Z., Easom, Eric E., Feng, Lisa, Hernandez, Vincent, Houston, Paul, Liu, Liang, Meewan, Maliwan, Mohan, Manisha, Rock, Fernando L., Sexton, Holly, Zhang, Suoming, Zhou, Yasheen, Wan, Baojie, Wang, Yuehong, Franzblau, Scott G., Woolhiser, Lisa, Gruppo, Veronica, Lenaerts, Anne J., O'Malley, Theresa, Parish, Tanya, Cooper, Christopher B., Waters, M. Gerard, Ma, Zhenkun, Ioerger, Thomas R., Sacchettini, James C., Rullas, Joaquín, Angulo-Barturen, Iñigo, Pérez-Herrán, Esther, Mendoza, Alfonso, Barros, David, Cusack, Stephen, Plattner, Jacob J., Alley, M. R. K.
Publicado no Antimicrob Agents Chemother (2016)