Phase II Metabolic Pathways of Spectinamide Antitubercular Agents: A Comparative Study of the Reactivity of 4-Substituted Pyridines to Glutathione Conjugation

Por Madhura, Dora B., Liu, Juiyu, Meibohm, Bernd, Lee, Richard E.
Publicado no Medchemcomm (2015)

Antitubercular nitrofuran isoxazolines with improved pharmacokinetic properties

Por Rakesh, Bruhn, David, Madhura, Dora B., Maddox, Marcus, Lee, Robin B., Trivedi, Ashit, Yang, Lei, Scherman, Michael S., Gilliland, Janet C., Gruppo, Veronica, McNeil, Michael R., Lenaerts, Anne J., Meibohm, Bernd, Lee, Richard E.
Publicado em 2012

Pentacyclic Nitrofurans with In Vivo Efficacy and Activity against Nonreplicating Mycobacterium tuberculosis

Por Rakesh, Bruhn, David F., Scherman, Michael S., Woolhiser, Lisa K., Madhura, Dora B., Maddox, Marcus M., Singh, Aman P., Lee, Robin B., Hurdle, Julian G., McNeil, Michael R., Lenaerts, Anne J., Meibohm, Bernd, Lee, Richard E.
Publicado em 2014

Aminomethyl Spectinomycins as Novel Therapeutics for Drug Resistant Respiratory Tract and Sexually Transmitted Bacterial Infections

Por Bruhn, David F., Waidyarachchi, Samanthi L., Madhura, Dora B., Shcherbakov, Dimitri, Zheng, Zhong, Liu, Jiuyu, Abdelrahman, Yasser M., Singh, Aman P., Duscha, Stefan, Rathi, Chetan, Lee, Robin B., Belland, Robert J., Meibohm, Bernd, Rosch, Jason W., Böttger, Erik C., Lee, Richard E.
Publicado no Sci Transl Med (2015)

Spectinamides: A New Class of Semisynthetic Anti-Tuberculosis Agents that Overcome Native Drug Efflux

Por Lee, Richard E., Hurdle, Julian G., Liu, Jiuyu, Bruhn, David F., Matt, Tanja, Scherman, Michael S., Vaddady, Pavan K, Zheng, Zhong, Qi, Jianjun, Akbergenov, Rashid, Das, Sourav, Madhura, Dora B., Rathi, Chetan, Trivedi, Ashit, Villellas, Cristina, Lee, Robin. B., Rakesh, Waidyarachchi, Samanthi L., Sun, Dianqing, McNeil, Michael R., Ainsa, Jose A., Boshoff, Helena I., Gonzalez-Juarrero, Mercedes, Meibohm, Bernd, Böttger, Erik C., Lenaerts, Anne J.
Publicado em 2014