Pentacyclic Nitrofurans with In Vivo Efficacy and Activity against Nonreplicating Mycobacterium tuberculosis

The reductively activated nitroaromatic class of antimicrobials, which include nitroimidazole and the more metabolically labile nitrofuran antitubercular agents, have demonstrated some potential for development as therapeutics against dormant TB bacilli. In previous studies, the pharmacokinetic prop...

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Detalhes bibliográficos
Main Authors: Rakesh, Bruhn, David F., Scherman, Michael S., Woolhiser, Lisa K., Madhura, Dora B., Maddox, Marcus M., Singh, Aman P., Lee, Robin B., Hurdle, Julian G., McNeil, Michael R., Lenaerts, Anne J., Meibohm, Bernd, Lee, Richard E.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3914891/
https://ncbi.nlm.nih.gov/pubmed/24505329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0087909
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