New agents for the treatment of drug-resistant Mycobacterium tuberculosis

Por Hoagland, Daniel, Liu, Jiuyu, Lee, Robin B., Lee, Richard E.
Publicado no Adv Drug Deliv Rev (2016)

Synthesis, Optimization and Structure-Activity Relationships of 3,5-Disubstituted Isoxazolines as New Anti-tuberculosis Agents

Por Rakesh, Dianqing Sun, Lee, Robin B., Tangallapally, Rajendra, Lee, Richard E.
Publicado em 2008

A Simple in vitro PK/PD Model System to Determine Time-Kill Curves of Drugs against Mycobacteria

Por Budha, Nageshwar R., Lee, Robin B., Hurdle, Julian G., Lee, Richard E., Meibohm, Bernd
Publicado em 2009

Spectinamides are effective partner agents for the treatment of tuberculosis in multiple mouse infection models

Por Robertson, Gregory T., Scherman, Michael S., Bruhn, David F., Liu, Jiuyu, Hastings, Courtney, McNeil, Michael R., Butler, Michelle M., Bowlin, Terry L., Lee, Robin B., Lee, Richard E., Lenaerts, Anne J.
Publicado no J Antimicrob Chemother (2017)

A microbiological assessment of novel nitrofuranylamides as anti-tuberculosis agents

Por Hurdle, Julian G., Lee, Robin B., Budha, Nageshwar R., Carson, Elizabeth I., Qi, Jianjun, Scherman, Michael S., Cho, Sang Hyun, McNeil, Michael R., Lenaerts, Anne J., Franzblau, Scott G., Meibohm, Bernd, Lee, Richard E.
Publicado em 2008

Antitubercular nitrofuran isoxazolines with improved pharmacokinetic properties

Por Rakesh, Bruhn, David, Madhura, Dora B., Maddox, Marcus, Lee, Robin B., Trivedi, Ashit, Yang, Lei, Scherman, Michael S., Gilliland, Janet C., Gruppo, Veronica, McNeil, Michael R., Lenaerts, Anne J., Meibohm, Bernd, Lee, Richard E.
Publicado em 2012

Pentacyclic Nitrofurans with In Vivo Efficacy and Activity against Nonreplicating Mycobacterium tuberculosis

Por Rakesh, Bruhn, David F., Scherman, Michael S., Woolhiser, Lisa K., Madhura, Dora B., Maddox, Marcus M., Singh, Aman P., Lee, Robin B., Hurdle, Julian G., McNeil, Michael R., Lenaerts, Anne J., Meibohm, Bernd, Lee, Richard E.
Publicado em 2014

Synthesis, Structure–Activity Relationship Studies, and Antibacterial Evaluation of 4-Chromanones and Chalcones, as Well as Olympicin A and Derivatives

Por Feng, Li, Maddox, Marcus M., Alam, Md. Zahidul, Tsutsumi, Lissa S., Narula, Gagandeep, Bruhn, David F., Wu, Xiaoqian, Sandhaus, Shayna, Lee, Robin B., Simmons, Charles J., Tse-Dinh, Yuk-Ching, Hurdle, Julian G., Lee, Richard E., Sun, Dianqing
Publicado em 2014

Aminomethyl Spectinomycins as Novel Therapeutics for Drug Resistant Respiratory Tract and Sexually Transmitted Bacterial Infections

Por Bruhn, David F., Waidyarachchi, Samanthi L., Madhura, Dora B., Shcherbakov, Dimitri, Zheng, Zhong, Liu, Jiuyu, Abdelrahman, Yasser M., Singh, Aman P., Duscha, Stefan, Rathi, Chetan, Lee, Robin B., Belland, Robert J., Meibohm, Bernd, Rosch, Jason W., Böttger, Erik C., Lee, Richard E.
Publicado no Sci Transl Med (2015)

The Structure-Activity Relationships of Spectinamide Antituberculosis agents; a Dissection of Ribosomal Inhibition and Native Efflux Avoidance Contributions

Por Liu, Jiuyu, Bruhn, David F., Lee, Robin. B., Zheng, Zhong, Janusic, Tanja, Scherbakov, Dimitri, Scherman, Michael S., Boshoff, Helena I., Das, Sourav, Rakesh, Waidyarachchi, Samanthi L., Brewer, Tiffany A., Gracia, Begoña, Yang, Lei, Bollinger, John, Robertson, Gregory T., Meibohm, Bernd, Lenaerts, Anne J., Ainsa, Jose, Böttger, Erik C., Lee, Richard E.
Publicado no ACS Infect Dis (2016)

Spectinamides: A New Class of Semisynthetic Anti-Tuberculosis Agents that Overcome Native Drug Efflux

Por Lee, Richard E., Hurdle, Julian G., Liu, Jiuyu, Bruhn, David F., Matt, Tanja, Scherman, Michael S., Vaddady, Pavan K, Zheng, Zhong, Qi, Jianjun, Akbergenov, Rashid, Das, Sourav, Madhura, Dora B., Rathi, Chetan, Trivedi, Ashit, Villellas, Cristina, Lee, Robin. B., Rakesh, Waidyarachchi, Samanthi L., Sun, Dianqing, McNeil, Michael R., Ainsa, Jose A., Boshoff, Helena I., Gonzalez-Juarrero, Mercedes, Meibohm, Bernd, Böttger, Erik C., Lenaerts, Anne J.
Publicado em 2014