Spectinamides are effective partner agents for the treatment of tuberculosis in multiple mouse infection models

Objectives: New drug regimens employing combinations of existing and experimental antimicrobial agents are needed to shorten treatment of tuberculosis (TB) in humans. The spectinamides are narrow-spectrum semisynthetic analogues of spectinomycin, modified to avoid intrinsic efflux by Mycobacterium t...

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Detalhes bibliográficos
Publicado no:J Antimicrob Chemother
Main Authors: Robertson, Gregory T., Scherman, Michael S., Bruhn, David F., Liu, Jiuyu, Hastings, Courtney, McNeil, Michael R., Butler, Michelle M., Bowlin, Terry L., Lee, Robin B., Lee, Richard E., Lenaerts, Anne J.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
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Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5400088/
https://ncbi.nlm.nih.gov/pubmed/27999020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jac/dkw467
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