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Tissue Penetration of a Novel Spectinamide Antibiotic for the Treatment of Tuberculosis
The in vivo biodistribution and pharmacokinetics of 1329, a novel spectinamide antibiotic with anti-tubercular activity, were studied during intravenous administration of an tritium-labeled compound for nine consecutive, 12-hourly doses to rats. Serial blood samples were collected after the first an...
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| Publicat a: | AAPS J |
|---|---|
| Autors principals: | , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Springer US
2016
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5256617/ https://ncbi.nlm.nih.gov/pubmed/26984832 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12248-016-9900-7 |
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