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Dynamic Time-Kill Curve Characterization of Spectinamide Antibiotics 1445 and 1599 for the Treatment of Tuberculosis

Spectinamides are a novel class of antibiotics under development for the treatment of MDR- and XDR-tuberculosis, with 1599 and 1445 as early lead candidates within this group. In order to evaluate and differentiate the pharmacological properties of these compounds and assist in candidate selection a...

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Bibliografiske detaljer
Udgivet i:Eur J Pharm Sci
Main Authors: Vaddady, Pavan K., Trivedi, Ashit, Rathi, Chetan, Madhura, Dora B., Liu, Jiuyu, Lee, Richard E., Meibohm, Bernd
Format: Artigo
Sprog:Inglês
Udgivet: 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6311108/
https://ncbi.nlm.nih.gov/pubmed/30419293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejps.2018.11.006
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