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Synthesis, Optimization and Structure-Activity Relationships of 3,5-Disubstituted Isoxazolines as New Anti-tuberculosis Agents

In the course of the development of a potent series of nitrofuranylamide anti-tuberculosis agents, we investigated if the exceptional activity resulted in part from the isoxazoline core and if it possessed any intrinsic anti-tuberculosis activity. This led to the discovery of an isoxazoline ester wi...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Rakesh, Dianqing Sun, Lee, Robin B., Tangallapally, Rajendra, Lee, Richard E.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2008
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2674295/
https://ncbi.nlm.nih.gov/pubmed/18524421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejmech.2008.04.007
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