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Synthesis and Investigation of Novel Spiro-isoxazolines as Anti-Cancer Agents
A series of structurally diverse 4-bromo spiro-isoxazolines possessing a variety of aromatic and aliphatic substituents at the 3 position, were synthesized through a 1,3-dipolar cycloaddition followed by intramolecular cyclization of a pendant hydroxyl or carboxylic acid group. The biochemical antip...
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| Veröffentlicht in: | Tetrahedron Lett |
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| Hauptverfasser: | , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4371604/ https://ncbi.nlm.nih.gov/pubmed/25821250 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tetlet.2015.02.059 |
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