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Oxonium Ion Mediated Synthesis of 4-Substituted Spiro-Isoxazolines
The stereoselective synthesis of 4-bromo-spiro-isoxazolines was achieved in one step through the bromination of various isoxazoles that contain a pendant alcohol or carboxylic acid functional group. Isoxazole bromination leads to a bromonium ion intermediate which opens either by neighboring oxygen...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2723812/ https://ncbi.nlm.nih.gov/pubmed/20140060 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tetlet.2008.11.053 |
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