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Synthesis, Characterization and Biological Evaluation of New 3,5-Disubstituted-Pyrazoline Derivatives as Potential Anti-Mycobacterium tuberculosis H37Ra Compounds

A total of fourteen pyrazoline derivatives were synthesized through cyclo-condensation reactions by chalcone derivatives with different types of semicarbazide. These compounds were characterized by IR, 1D-NMR ((1)H, (13)C and Distortionless Enhancement by Polarization Transfer - DEPT-135) and 2D-NMR...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Wong, Kok Tong, Osman, Hasnah, Parumasivam, Thaigarajan, Supratman, Unang, Che Omar, Mohammad Tasyriq, Azmi, Mohamad Nurul
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8038544/
https://ncbi.nlm.nih.gov/pubmed/33916423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules26072081
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