Increased Sensitivity to Oxidative Challenges Associated with topA Deletion in Escherichia coli

Por Tse-Dinh, Yuk-Ching
Publicado em 2000

Bacterial topoisomerase I as a target for discovery of antibacterial compounds

Por Tse-Dinh, Yuk-Ching
Publicado em 2009

Targeting bacterial topoisomerase I to meet the challenge of finding new antibiotics

Por Tse-Dinh, Yuk-Ching
Publicado no Future Med Chem (2015)

The role of the Zn(II) binding domain in the mechanism of E. coli DNA topoisomerase I

Por Ahumada, Adriana, Tse-Dinh, Yuk-Ching
Publicado em 2002

Residues of E. coli topoisomerase I conserved for interaction with a specific cytosine base to facilitate DNA cleavage

Por Narula, Gagandeep, Tse-Dinh, Yuk-Ching
Publicado em 2012

Isolation and Quantitation of Topoisomerase Complexes Accumulated on Escherichia coli Chromosomal DNA

Por Aedo, Sandra, Tse-Dinh, Yuk-Ching
Publicado em 2012

SbcCD-Mediated Processing of Covalent Gyrase-DNA Complex in Escherichia coli

Por Aedo, Sandra, Tse-Dinh, Yuk-Ching
Publicado em 2013

Analysis of RuvABC and RecG Involvement in the Escherichia coli Response to the Covalent Topoisomerase-DNA Complex

Por Sutherland, Jeanette H., Tse-Dinh, Yuk-Ching
Publicado em 2010

Crystal structure of a covalent intermediate in DNA cleavage and rejoining by Escherichia coli DNA topoisomerase I

Por Zhang, Zhongtao, Cheng, Bokun, Tse-Dinh, Yuk-Ching
Publicado em 2011

Distinct Mechanism Evolved for Mycobacterial RNA Polymerase and Topoisomerase I Protein-Protein Interaction

Por Banda, Srikanth, Cao, Nan, Tse-Dinh, Yuk-Ching
Publicado no J Mol Biol (2017)

Mechanism of Type IA Topoisomerases

Por Dasgupta, Tumpa, Ferdous, Shomita, Tse-Dinh, Yuk-Ching
Publicado no Molecules (2020)

Type IA Topoisomerases as Targets for Infectious Disease Treatments

Por Seddek, Ahmed, Annamalai, Thirunavukkarasu, Tse-Dinh, Yuk-Ching
Publicado no Microorganisms (2021)

Mutation adjacent to the active site tyrosine can enhance DNA cleavage and cell killing by the TOPRIM Gly to Ser mutant of bacterial topoisomerase I

Por Cheng, Bokun, Sorokin, Elena P., Tse-Dinh, Yuk-Ching
Publicado em 2008

Resistance to topoisomerase cleavage complex induced lethality in Escherichia coli via titration of transcription regulators PurR and FNR

Por Liu, I-Fen, Aedo, Sandra, Tse-Dinh, Yuk-Ching
Publicado em 2011

Discovery of novel bacterial topoisomerase I inhibitors by use of in silico docking and in vitro assays

Por Sandhaus, Shayna, Chapagain, Prem P., Tse-Dinh, Yuk-Ching
Publicado no Sci Rep (2018)

Direct Observation of Topoisomerase IA Gate Dynamics

Por Mills, Maria, Tse-Dinh, Yuk-Ching, Neuman, Keir C.
Publicado no Nat Struct Mol Biol (2018)

Analysis of DNA relaxation and cleavage activities of recombinant Mycobacterium tuberculosis DNA topoisomerase I from a new expression and purification protocol

Por Annamalai, Thirunavukkarasu, Dani, Neil, Cheng, Bokun, Tse-Dinh, Yuk-Ching
Publicado em 2009

Investigating direct interaction between Escherichia coli topoisomerase I and RecA

Por Banda, Srikanth, Tiwari, Purushottam Babu, Darici, Yesim, Tse-Dinh, Yuk-Ching
Publicado no Gene (2016)

EXTH-09. TDP1/TOP1 RATIO AS A PREDICTIVE INDICATOR FOR THE RESPONSE OF GLIOBLASTOMA CANCER CELLS TO IRINOTECAN TREATMENT

Por Wang, Wenjie, Silva, Monica Rodriguez, Chambers, Jeremy, Tse-Dinh, Yuk-Ching
Publicado no Neuro Oncol (2017)

BACTERIAL CELL KILLING MEDIATED BY TOPOISOMERASE I DNA CLEAVAGE ACTIVITY

Por Cheng, Bokun, Shukla, Shikha, Vasunilashorn, Sarinnapha, Mukhopadhyay, Somshuvra, Tse-Dinh, Yuk-Ching
Publicado em 2005