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Direct Observation of Topoisomerase IA Gate Dynamics
Type IA topoisomerases cleave single-stranded DNA and relieve negative supercoils in discrete steps corresponding to the passage of the intact DNA strand through the cleaved strand. Although it is assumed type IA topoisomerases accomplish this strand passage via a protein-mediated DNA gate, opening...
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| Publicado no: | Nat Struct Mol Biol |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6379066/ https://ncbi.nlm.nih.gov/pubmed/30478267 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41594-018-0158-x |
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