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Microheterogeneity of Topoisomerase IA/IB and Their DNA-Bound States

[Image: see text] Topoisomerases are important complex enzymes that modulate DNA topology to maintain chromosome superstructure and integrity. These enzymes are involved in many cellular processes that resolve specific DNA superstructures and intermediates. The low abundance combined with the biolog...

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Veröffentlicht in:ACS Omega
Hauptverfasser: Jeanne Dit Fouque, Kevin, Garabedian, Alyssa, Leng, Fenfei, Tse-Dinh, Yuk-Ching, Fernandez-Lima, Francisco
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Chemical Society 2019
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6396120/
https://ncbi.nlm.nih.gov/pubmed/30842985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.8b02887
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