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Targeting bacterial topoisomerase I to meet the challenge of finding new antibiotics

Resistance of bacterial pathogens to current antibiotics has grown to be an urgent crisis. Approaches to overcome this challenge include identification of novel targets for discovery of new antibiotics. Bacterial topoisomerase I is present in all bacterial pathogens as a potential target for bacteri...

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Vydáno v:Future Med Chem
Hlavní autor: Tse-Dinh, Yuk-Ching
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4415981/
https://ncbi.nlm.nih.gov/pubmed/25875873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4155/fmc.14.157
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