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Resistance to topoisomerase cleavage complex induced lethality in Escherichia coli via titration of transcription regulators PurR and FNR

BACKGROUND: Accumulation of gyrase cleavage complex in Escherichia coli from the action of quinolone antibiotics induces an oxidative damage cell death pathway. The oxidative cell death pathway has also been shown to be involved in the lethality following accumulation of cleavage complex formed by b...

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Main Authors: Liu, I-Fen, Aedo, Sandra, Tse-Dinh, Yuk-Ching
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3266220/
https://ncbi.nlm.nih.gov/pubmed/22152010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2180-11-261
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