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Resistance to topoisomerase cleavage complex induced lethality in Escherichia coli via titration of transcription regulators PurR and FNR

BACKGROUND: Accumulation of gyrase cleavage complex in Escherichia coli from the action of quinolone antibiotics induces an oxidative damage cell death pathway. The oxidative cell death pathway has also been shown to be involved in the lethality following accumulation of cleavage complex formed by b...

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Autori principali: Liu, I-Fen, Aedo, Sandra, Tse-Dinh, Yuk-Ching
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3266220/
https://ncbi.nlm.nih.gov/pubmed/22152010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2180-11-261
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