Asp to Asn substitution at the first position of the DxD TOPRIM motif of recombinant bacterial topoisomerase I is extremely lethal to E. coli

Những quyển sách tương tự

• Mutation adjacent to the active site tyrosine can enhance DNA cleavage and cell killing by the TOPRIM Gly to Ser mutant of bacterial topoisomerase I
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  Được phát hành: (2008)
• Inhibition of Mg(2+) binding and DNA religation by bacterial topoisomerase I via introduction of an additional positive charge into the active site region
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  Được phát hành: (2008)
• The Strictly Conserved Arg-321 Residue in the Active Site of Escherichia coli Topoisomerase I Plays a Critical Role in DNA Rejoining
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  Được phát hành: (2011)
• Resistance to topoisomerase cleavage complex induced lethality in Escherichia coli via titration of transcription regulators PurR and FNR
  Bằng: Liu, I-Fen, et al.
  Được phát hành: (2011)
• Analysis of DNA relaxation and cleavage activities of recombinant Mycobacterium tuberculosis DNA topoisomerase I from a new expression and purification protocol
  Bằng: Annamalai, Thirunavukkarasu, et al.
  Được phát hành: (2009)