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A Simple in vitro PK/PD Model System to Determine Time-Kill Curves of Drugs against Mycobacteria
In vivo tuberculosis is exposed to continually changing drug concentrations for which static minimum inhibitory concentration (MIC) testing may be a poor surrogate. While in vitro approaches to determine time-kill curves for antibiotics have been widely applied in assessing antimicrobial activity ag...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2783979/ https://ncbi.nlm.nih.gov/pubmed/19748318 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tube.2009.08.002 |
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