Discovery, Synthesis, and Biological Evaluation of Piperidinol analogs With Anti-tuberculosis Activity

Direct anti-tuberculosis screening of commercially available compound libraries identified a novel piperidinol with interesting anti-tuberculosis activity and drug like characteristics. To generate a structure activity relationship about this hit a 22 member optimization library was generated using...

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Detaylı Bibliyografya
Asıl Yazarlar: Sun, Dianqing, Scherman, Michael S., Jones, Victoria, Hurdle, Julian G., Woolhiser, Lisa K., Knudson, Susan E., Lenaerts, Anne J., Slayden, Richard A., McNeil, Michael R., Lee, Richard E.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2009
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Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2756498/
https://ncbi.nlm.nih.gov/pubmed/19386501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2009.04.005
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