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Solid-Phase Synthesis and Biological Evaluation of a Uridinyl Branched Peptide Urea Library

A 1000-member uridinyl branched peptide library was synthesized on PS-DES support using IRORI technology. High-throughput screening of this library for anti-tuberculosis activity identified several members with a MIC(90) value of 12.5 μg/mL.

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Detalhes bibliográficos
Main Authors: Sun, Dianqing, Jones, Victoria, Carson, Elizabeth I., Lee, Robin E. B., Scherman, Michael S., McNeil, Michael R., Lee, Richard E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2140236/
https://ncbi.nlm.nih.gov/pubmed/17962016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2007.09.097
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