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Solid-Phase Synthesis of C-Terminal Peptide Libraries for Studying the Specificity of Enzymatic Protein Prenylation

Prenylation is an essential post-translational modification in all eukaryotes. Here we describe the synthesis of a 340-member library of peptides containing free C-termini on cellulose membranes. The resulting library was then used to probe the specificity of protein farnesyltransferase from S. cere...

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Detaylı Bibliyografya
Asıl Yazarlar: Wang, Yen-Chih, Distefano, Mark D.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2012
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3682486/
https://ncbi.nlm.nih.gov/pubmed/22783549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c2cc31713c
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