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A general strategy for the preparation of C-terminal peptide α-ketoacids by solid phase peptide synthesis
A new cyanosulfur-ylide based linker makes possible the synthesis of C-terminal peptide α-ketoacids by solid phase synthesis. The preparation of the requisite linker and its application to a variety of C-terminal peptide α-ketoacids with unprotected side chains is reported.
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2907649/ https://ncbi.nlm.nih.gov/pubmed/19462032 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/b901198f |
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