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A general strategy for the preparation of C-terminal peptide α-ketoacids by solid phase peptide synthesis

A new cyanosulfur-ylide based linker makes possible the synthesis of C-terminal peptide α-ketoacids by solid phase synthesis. The preparation of the requisite linker and its application to a variety of C-terminal peptide α-ketoacids with unprotected side chains is reported.

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Bibliografski detalji
Glavni autori: Ju, Lei, Bode, Jeffrey W.
Format: Artigo
Jezik:Inglês
Izdano: 2009
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2907649/
https://ncbi.nlm.nih.gov/pubmed/19462032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/b901198f
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