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Effect of Microwave Radiation on Enzymatic and Chemical Peptide Bond Synthesis on Solid Phase

Peptide bond synthesis was performed on PEGA beads under microwave radiations. Classical chemical coupling as well as thermolysin catalyzed synthesis was studied, and the effect of microwave radiations on reaction kinetics, beads' integrity, and enzyme activity was assessed. Results demonstrate...

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Detalhes bibliográficos
Main Authors: Basso, Alessandra, Sinigoi, Loris, Gardossi, Lucia, Flitsch, Sabine
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2915653/
https://ncbi.nlm.nih.gov/pubmed/20721296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2009/362482
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