Effect of Microwave Radiation on Enzymatic and Chemical Peptide Bond Synthesis on Solid Phase

Peptide bond synthesis was performed on PEGA beads under microwave radiations. Classical chemical coupling as well as thermolysin catalyzed synthesis was studied, and the effect of microwave radiations on reaction kinetics, beads' integrity, and enzyme activity was assessed. Results demonstrate...

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Bibliographic Details
Main Authors: Basso, Alessandra, Sinigoi, Loris, Gardossi, Lucia, Flitsch, Sabine
Format: Artigo
Language:Inglês
Published: Hindawi Publishing Corporation 2009
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2915653/
https://ncbi.nlm.nih.gov/pubmed/20721296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2009/362482
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