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Solid-Phase Synthesis and Biological Evaluation of a Uridinyl Branched Peptide Urea Library

A 1000-member uridinyl branched peptide library was synthesized on PS-DES support using IRORI technology. High-throughput screening of this library for anti-tuberculosis activity identified several members with a MIC(90) value of 12.5 μg/mL.

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Sun, Dianqing, Jones, Victoria, Carson, Elizabeth I., Lee, Robin E. B., Scherman, Michael S., McNeil, Michael R., Lee, Richard E.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2007
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2140236/
https://ncbi.nlm.nih.gov/pubmed/17962016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2007.09.097
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