Mouse Model for Efficacy Testing of Antituberculosis Agents via Intrapulmonary Delivery

Here we describe an experimental murine model that allows for aerosolized antituberculosis drug efficacy testing. Intrapulmonary aerosol delivery of isoniazid, capreomycin, and amikacin to mice with pulmonary infection of Mycobacterium tuberculosis demonstrated efficacy in reducing pulmonary bacteri...

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Bibliografiska uppgifter
Huvudupphovsmän: Gonzalez-Juarrero, Mercedes, Woolhiser, Lisa K., Brooks, Elizabeth, DeGroote, Mary Ann, Lenaerts, Anne J.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2012
Ämnen:
Experimental Therapeutics
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3393411/
https://ncbi.nlm.nih.gov/pubmed/22547626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00464-12
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