Mouse Model for Efficacy Testing of Antituberculosis Agents via Intrapulmonary Delivery

Here we describe an experimental murine model that allows for aerosolized antituberculosis drug efficacy testing. Intrapulmonary aerosol delivery of isoniazid, capreomycin, and amikacin to mice with pulmonary infection of Mycobacterium tuberculosis demonstrated efficacy in reducing pulmonary bacteri...

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Bibliografiset tiedot
Päätekijät: Gonzalez-Juarrero, Mercedes, Woolhiser, Lisa K., Brooks, Elizabeth, DeGroote, Mary Ann, Lenaerts, Anne J.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Microbiology 2012
Aiheet:
Experimental Therapeutics
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3393411/
https://ncbi.nlm.nih.gov/pubmed/22547626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00464-12
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