Mouse Model for Efficacy Testing of Antituberculosis Agents via Intrapulmonary Delivery

Here we describe an experimental murine model that allows for aerosolized antituberculosis drug efficacy testing. Intrapulmonary aerosol delivery of isoniazid, capreomycin, and amikacin to mice with pulmonary infection of Mycobacterium tuberculosis demonstrated efficacy in reducing pulmonary bacteri...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Gonzalez-Juarrero, Mercedes, Woolhiser, Lisa K., Brooks, Elizabeth, DeGroote, Mary Ann, Lenaerts, Anne J.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology 2012
Gaiak:
Experimental Therapeutics
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3393411/
https://ncbi.nlm.nih.gov/pubmed/22547626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00464-12
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