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Mouse Model for Efficacy Testing of Antituberculosis Agents via Intrapulmonary Delivery
Here we describe an experimental murine model that allows for aerosolized antituberculosis drug efficacy testing. Intrapulmonary aerosol delivery of isoniazid, capreomycin, and amikacin to mice with pulmonary infection of Mycobacterium tuberculosis demonstrated efficacy in reducing pulmonary bacteri...
में बचाया:
| मुख्य लेखकों: | , , , , |
|---|---|
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
American Society for Microbiology
2012
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3393411/ https://ncbi.nlm.nih.gov/pubmed/22547626 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00464-12 |
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