Efficacy of FK463, a New Lipopeptide Antifungal Agent, in Mouse Models of Disseminated Candidiasis and Aspergillosis

The efficacy of intravenous injection of FK463, a novel water-soluble lipopeptide, was evaluated in mouse models of disseminated candidiasis and aspergillosis and was compared with those of fluconazole (FLCZ) and amphotericin B (AMPH-B). In the candidiasis model, FK463 significantly prolonged the su...

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Main Authors: Ikeda, Fumiaki, Wakai, Yoshimi, Matsumoto, Satoru, Maki, Katsuyuki, Watabe, Etsuko, Tawara, Shuichi, Goto, Toshio, Watanabe, Yuji, Matsumoto, Fumio, Kuwahara, Shogo
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2000
Fag:
Experimental Therapeutics
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC89735/
https://ncbi.nlm.nih.gov/pubmed/10681327
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