Compartmental Pharmacokinetics and Tissue Distribution of the Antifungal Echinocandin Lipopeptide Micafungin (FK463) in Rabbits

The plasma pharmacokinetics and tissue distribution of the novel antifungal echinocandin-like lipopeptide micafungin (FK463) were investigated in healthy rabbits. Cohorts of three animals each received micafungin at 0.5, 1, and 2 mg/kg of body weight intravenously once daily for a total of 8 days. S...

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Main Authors: Groll, Andreas H., Mickiene, Diana, Petraitis, Vidmantas, Petraitiene, Ruta, Ibrahim, Khalid H., Piscitelli, Stephen C., Bekersky, Ihor, Walsh, Thomas J.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2001
Assuntos:
Pharmacology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC90832/
https://ncbi.nlm.nih.gov/pubmed/11709303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.45.12.3322-3327.2001
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