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Prophylactic Effect of FK463, a Novel Antifungal Lipopeptide, against Pneumocystis carinii Infection in Mice

The prophylactic effect of FK463, a new water-soluble echinocandin-like lipopeptide with inhibitory activity against 1,3-β-d-glucan synthase, against Pneumocystis carinii infection was investigated with the severe combined immunodeficient (SCID) mouse model. Treatment with FK463, pentamidine, and sa...

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Auteurs principaux: Ito, Mamoru, Nozu, Ryoko, Kuramochi, Takashi, Eguchi, Natsuko, Suzuki, Shuzo, Hioki, Kyoji, Itoh, Toshio, Ikeda, Fumiaki
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2000
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC90055/
https://ncbi.nlm.nih.gov/pubmed/10952565
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