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Importance of Confirming Data on the In Vivo Efficacy of Novel Antibacterial Drug Regimens against Various Strains of Mycobacterium tuberculosis

In preclinical testing of antituberculosis drugs, laboratory-adapted strains of Mycobacterium tuberculosis are usually used both for in vitro and in vivo studies. However, it is unknown whether the heterogeneity of M. tuberculosis stocks used by various laboratories can result in different outcomes...

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Detalhes bibliográficos
Main Authors: De Groote, Mary A., Gruppo, Veronica, Woolhiser, Lisa K., Orme, Ian M., Gilliland, Janet C., Lenaerts, Anne J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3264252/
https://ncbi.nlm.nih.gov/pubmed/22143517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.05701-11
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