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Bayesian Models Leveraging Bioactivity and Cytotoxicity Information for Drug Discovery
Identification of unique leads represents a significant challenge in drug discovery. This hurdle is magnified in neglected diseases such as tuberculosis. We have leveraged public high-throughput screening (HTS) data, to experimentally validate virtual screening approach employing Bayesian models bui...
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| Autori principali: | , , , , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2013
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3607962/ https://ncbi.nlm.nih.gov/pubmed/23521795 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2013.01.011 |
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