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Naïve Bayesian Models for Vero Cell Cytotoxicity

PURPOSE: To advance translational research of potential therapeutic small molecules against infectious microbes, the compounds must display a relative lack of mammalian cell cytotoxicity. Vero cell cytotoxicity (CC(50)) is a common initial assay for this metric. We explored the development of naïve...

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Bibliographic Details
Published in:Pharm Res
Main Authors: Perryman, Alexander L., Patel, Jimmy S., Russo, Riccardo, Singleton, Eric, Connell, Nancy, Ekins, Sean, Freundlich, Joel S.
Format: Artigo
Language:Inglês
Published: 2018
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7768703/
https://ncbi.nlm.nih.gov/pubmed/29959603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11095-018-2439-9
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