UTILIZTION OF THE SUZUKI COUPLING TO ENHANCE THE ANTITUBERCULOSIS ACTIVITY OF ARYL OXAZOLES

Por Moraski, Garrett C., Franzblau, Scott G., Miller, Marvin J.
Publicado em 2010

Bactericidal Activity of an Imidazo[1, 2-a]pyridine Using a Mouse M. tuberculosis Infection Model

Por Cheng, Yong, Moraski, Garrett C., Cramer, Jeffrey, Miller, Marvin J., Schorey, Jeffrey S.
Publicado em 2014

One Step Syntheses of Nitrofuranyl Benzimidazoles that are Active Against Multi-Drug Resistant Bacteria

Por Moraski, Garrett C., Thanassi, Jane A., Podos, Steven D., Pucci, Michael J., Miller, Marvin J.
Publicado em 2011

Structure-Activity Relationship of New Antituberculosis Agents Derived from Oxazoline and Oxazole Esters

Por Moraski, Garrett C., Chang, Mayland, Villegas-Estrada, Adriel, Franzblau, Scott G., Möllmann, Ute, Miller, Marvin J.
Publicado em 2010

Scaffold-switching: An exploration of 5,6-fused bicyclic heteroaromatics systems to afford antituberculosis activity akin to the imidazo[1,2-a]pyridine-3-carboxylates

Por Moraski, Garrett C., Oliver, Allen G., Markley, Lowell D., Cho, Sanghyun, Franzblau, Scott G., Miller, Marvin J.
Publicado em 2014

Advent of Imidazo[1,2-a]pyridine-3-carboxamides with Potent Multi- and Extended Drug Resistant Antituberculosis Activity

Por Moraski, Garrett C., Markley, Lowell D., Hipskind, Philip A., Boshoff, Helena, Cho, Sanghyun, Franzblau, Scott G., Miller, Marvin J.
Publicado em 2011

A Dual Read-Out Assay to Evaluate the Potency of Compounds Active against Mycobacterium tuberculosis

Por Ollinger, Juliane, Bailey, Mai Ann, Moraski, Garrett C., Casey, Allen, Florio, Stephanie, Alling, Torey, Miller, Marvin J., Parish, Tanya
Publicado em 2013

N-((1-Benzyl-1H-1,2,3-triazol-4-yl)methyl)arylamide as a New Scaffold that Provides Rapid Access to Antimicrotubule Agents: Synthesis and Evaluation of Antiproliferative Activity A...

Por Stefely, Jonathan A., Palchaudhuri, Rahul, Miller, Patricia A., Peterson, Rebecca J., Moraski, Garrett C., Hergenrother, Paul J., Miller, Marvin J.
Publicado em 2010

Generation and exploration of new classes of antitubercular agents: The optimization of oxazolines, oxazoles, thiazolines, thiazoles to imidazo[1,2-a]pyridines and isomeric 5,6-fus...

Por Moraski, Garrett C., Markley, Lowell D., Chang, Mayland, Cho, Sanghyun, Franzblau, Scott G., Hwang, Chang Hwa, Boshoff, Helena, Miller, Marvin J.
Publicado em 2012

Syntheses and biological studies of novel spiropiperazinyl oxazolidinone antibacterial agents using a spirocyclic diene derived acylnitroso Diels Alder reaction

Por Ji, Cheng, Lin, Weimin, Moraski, Garrett C., Thanassi, Jane A., Pucci, Michael J., Franzblau, Scott G., Möllmann, Ute, Miller, Marvin J.
Publicado em 2012

Thiolates Chemically Induce Redox Activation of BTZ043 and Related Potent Nitro Aromatic Anti-Tuberculosis Agents

Por Tiwari, Rohit, Moraski, Garrett C., Krchňák, Viktor, Miller, Patricia A., Colon-Martinez, Mariangelli, Herrero, Eliza, Oliver, Allen G., Miller, Marvin J.
Publicado em 2013

Imidazo[1,2-a]Pyridine-3-Carboxamides Are Active Antimicrobial Agents against Mycobacterium avium Infection In Vivo

Por Moraski, Garrett C., Cheng, Yong, Cho, Sanghyun, Cramer, Jeffrey W., Godfrey, Alexander, Masquelin, Thierry, Franzblau, Scott G., Miller, Marvin J., Schorey, Jeffery
Publicado no Antimicrob Agents Chemother (2016)

Unusual Peroxide-Dependent, Heme-Transforming Reaction Catalyzed by HemQ

Por Celis, Arianna I., Streit, Bennett R., Moraski, Garrett C., Kant, Ravi, Lash, Timothy D., Lukat-Rodgers, Gudrun S., Rodgers, Kenton R., DuBois, Jennifer L.
Publicado no Biochemistry (2015)

Advancement of Imidazo[1,2-a]pyridines with Improved Pharmacokinetics and nM Activity vs. Mycobacterium tuberculosis

Por Moraski, Garrett C., Markley, Lowell D., Cramer, Jeffrey, Hipskind, Philip A., Boshoff, Helena, Bailey, Mai A., Alling, Torey, Ollinger, Juliane, Parish, Tanya, Miller, Marvin J.
Publicado em 2013

A Structure-Based Mechanism for Oxidative Decarboxylation Reactions Mediated by Amino Acids and Heme Propionates in Coproheme Decarboxylase (HemQ)

Por Celis, Arianna I., Gauss, George H., Streit, Bennett R., Shisler, Krista, Moraski, Garrett C., Rodgers, Kenton R., Lukat-Rodgers, Gudrun S., Peters, John W., DuBois, Jennifer L.
Publicado no J Am Chem Soc (2017)

Putting Tuberculosis (TB) To Rest: Transformation of the Sleep Aid, Ambien, and “Anagrams” Generated Potent Antituberculosis Agents

Por Moraski, Garrett C., Miller, Patricia A., Bailey, Mai Ann, Ollinger, Juliane, Parish, Tanya, Boshoff, Helena I., Cho, Sanghyun, Anderson, Jeffery R., Mulugeta, Surafel, Franzblau, Scott G., Miller, Marvin J.
Publicado no ACS Infect Dis (2014)